| No | Name | Formula | Industrial Use | Taste & flavor |
| 1 | Indole | ( C8H7N )
1350 |
Drug Intermediate,
Pesticides |
septic-like flavor |
| 2 | Para Cymene | ( C10H14 ) | Food flavor & drug intermediate | Jeera |
Drug Intermediates
INDOLE
Indole is used as an electron donor moiety in synthesizing dyes for organic photovoltaics.The Indole nucleus is an important element of many natural and synthetic molecules with significant biological activity. This review covers some of the relevant and recent achievements in the biological chemical and pharmacological activity of important indole derivatives in the area of drug discovery and analysis.
Indole & their derivatives are promising agents tuberculosis, malaria, diabetes, cancer, migraines, convulsions, hypertension, bacterial infection of methicillin resistant and even eye viruses.
| Product Name | 1H-Indole |
| Synonyms | 3-Benzopyrrole, ketole,1H-benzazole |
| Empirical Formula | C8H7N |
| Molecular Weight | 117.15 GM/MOL |
| Odar | Strong MothBall Naphthalene |
| Appearance | White Crystals |
| Purity | 99.5 % Minimum |
| Boiling Point | 254’C |
| Melting point | 51-54’C |
| CAS No | 120-72-9 |
| Packing | 1kg, 25kg |
| Description | Indole is an aromatic heterocyclic organic compound. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. Indole is widely distributed in the natural environment and can be produced by a variety of bacteria. |
Indole Alkaloids
Reserpine
Antihypertensive – to treat agitated psychotic conditions
Vinca alkaloids
Anticancer agents.
Ergot Alkaloids
1- Ergometrine – to prevent bleeding after childbirth ( smooth muscle constriction effect ).
2 – Ergotamine – Used in Migraine
Indole Drug examples
BIOLOGICAL IMPORTANCE OF INDOLE
As antimicrobials
As anti-inflammatory agents
As antitumor agents
As antiviral agents
As hypocholesterolemic agent
As anticancer agents
As antihistamines
As antioxidants
As anti-diabetic agents
As antiparkinsonian agents
General Uses of Indole
It is generally used as Drug intermediate, Agrochemical, Perfumery chemicals
Drugs
Indomethacin
Ergotamine
Frovatriptan
Ondansetron
Tadalafil
Medical Uses Of Indole
Para Cymene
p-Cymene is a naturally occurring aromatic organic compound. It is classified as an alkylbenzene related to monoterpene. Its structure consists of a benzene ring para-substituted with a methyl group and an isopropyl group. p-Cymene is insoluble in water, but miscible with organic solvents.
| Product Name | Para Cymene |
| Synonyms | para-Cymene,4-Isopropyltoluene,4-Methylcumene, P Cymene |
| Empirical Formula | C10H14 |
| Cas No | 99-87-6 |
| Molar Mass | 134.222 g.mol-1 |
| Density | 0.857 g/m3 |
| Flash point | 47 C |
| Boiling point | 177 C |
| Melting point | – 68 C |
| Solubility in water | 23.4 MG/L |
| Odar | Fresh citrus |
| Appearance | Colorless liquid |
| Storage | Store in cool, dry places in tightly sealed countries, Protect the head light. |
| Shelf Life | 12 Months |
| Packings | 100kg, 200kg Drum. |
Products & Informations
p-Cymene is transparent liquid, found in essential oils, and has a tang of terpenes with orange odor or carrot odor. It can be extracted from Dipentene on the reactions of dehydrogenation and disproportionation by Raney nickel or Pd/C as catalyst. In this method, it is easy to separate and have a higher yield than alkylation by Toluene. The great quality of p-Cymene used as material to synthesize Tonalide.
APPLICATIONS & USES
- the great quality of p-Cymene used as material to synthesis Tonalide
- food flavors
- flavors of daily products, such as soaps, cleaning solvent
- pharmaceutical ingredients, has expectorant, cough efficacy